整合素相關(guān)蛋白 (IAP/CD47) 激動(dòng)劑肽 4N1K (KRFYVVMWKK)，源自血小板反應(yīng)蛋白-1 (TS1) 的細(xì)胞結(jié)合域。該肽已被證明可以刺激依賴于整聯(lián)蛋白的細(xì)胞功能，包括血小板聚集。

Integrin-associated protein (IAP/CD47) agonist peptide, 4N1K (KRFYVVMWKK), derived from the cell binding domain of thrombospondin-1 (TS1). The peptide has been shown to stimulate integrin-dependent cell functions, including platelet aggregation.

編號(hào): 190917

中文名稱: [Lys1015, 1024]-Thrombospondin-1(1015-1024), human

英文名: [Lys1015, 1024]-Thrombospondin-1(1015-1024), human

CAS號(hào): 178921-95-4

單字母: H2N-KRFYVVMWKK-OH

三字母: H2N-Lys-Arg-Phe-Tyr-Val-Val-Met-Trp-Lys-Lys-COOH

氨基酸個(gè)數(shù): 10

分子式: C68H105N17O12S1

平均分子量: 1384.73

精確分子量: 1383.78

等電點(diǎn)(PI): 11.95

pH=7.0時(shí)的凈電荷數(shù): 4.97

平均親水性: -0.16

疏水性值: -0.49

來源: 人工化學(xué)合成，僅限科學(xué)研究使用，不得用于人體。

純度: 95%、98%

鹽體系: 可選TFA、HAc、HCl或其它

生成周期: 2-3周

儲(chǔ)存條件: 負(fù)80℃至負(fù)20℃

標(biāo)簽: 血小板反應(yīng)素

文獻(xiàn)：

DOI 名稱

10.1182/blood-2002-11-3483 Involvement of a CD47-dependent pathway in platelet adhesion on inflamed vascular endothelium under flow 下載

10.1074/jbc.M302194200 Thrombospondin-bound integrin-associated protein (CD47) physically and functionally modifies integrin alphaIIbbeta3 by its extracellular domain 下載

10.1083/jcb.135.2.533 Thrombospondin modulates alpha v beta 3 function through integrin-associated protein 下載

10.1091/mbc.9.4.865 The thrombospondin receptor CD47 (IAP) modulates and associates with alpha2 beta1 integrin in vascular smooth muscle cells 下載

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